Endocrine Abstracts

Background and Objectives: The differential diagnosis between arginine vasopressin (AVP) deficiency (AVP-D, formerly known as central diabetes insipidus) and primary polydipsia (PP) remains challenging. To date, the method with the highest diagnostic accuracy is osmotically-stimulated copeptin – a surrogate marker of AVP – using hypertonic saline infusion. However, this method is often limited to experienced hospitals, requires close monitoring, and may be cumbersome...